Increased glutamate transmission onto dorsal striatum spiny projection neurons in Pink1 knockout rats

Loss-of-function PTEN Induced Kinase 1 (PINK1) mutations cause early-onset familial Parkinson’s disease (PD) with similar clinical and neuropathological characteristics as idiopathic PD. While Pink1 knockout (KO) rats have mitochondrial dysfunction, locomotor deficits, and α-synuclein aggregates in...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Neurobiol Dis
Main Authors: Creed, Rose B., Roberts, Rosalinda C., Farmer, Charlene B., McMahon, Lori L., Goldberg, Matthew S.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7908817/
https://ncbi.nlm.nih.gov/pubmed/33387634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.105246
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker