Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses

The nuclear receptor (NR) subclass, retinoid X receptors (RXRs), exert immunomodulatory functions that control inflammation and metabolism via homodimers and heterodimers, with several other NRs, including retinoic acid receptors. IRX4204 is a novel, highly specific RXR agonist in clinical trials th...

詳細記述

保存先:
書誌詳細
出版年:Blood
主要な著者: Thangavelu, Govindarajan, Wang, Chao, Loschi, Michael, Saha, Asim, Osborn, Mark J., Furlan, Scott N., Aoyama, Kazutoshi, McDonald-Hyman, Cameron, Aguilar, Ethan G., Janesick, Amanda S., Chandraratna, Roshantha A., Refaeli, Yosef, Panoskaltsis-Mortari, Angela, MacDonald, Kelli P., Hill, Geoffrey R., Zeiser, Robert, Maillard, Ivan, Serody, Jonathan S., Murphy, William J., Munn, David H., Blumberg, Bruce, Brown, Chrysothemis, Kuchroo, Vijay, Kean, Leslie S., Hippen, Keli L., Noelle, Randolph J., Blazar, Bruce R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2021
主題:
Transplantation
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907720/
https://ncbi.nlm.nih.gov/pubmed/32976550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005628
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料