Combined kinesin-1 and kinesin-3 activity drives axonal trafficking of TrkB receptors in Rab6 carriers

Neurons depend on proper localization of neurotrophic receptors in their distal processes for their function. The Trk family of neurotrophin receptors controls neuronal survival, differentiation, and remodeling and are well known to function as retrograde signal carriers transported from the distal...

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Bibliographic Details
Published in:Dev Cell
Main Authors: Zahavi, Eitan Erez, Hummel, Jessica J.A., Han, Yuhao, Bar, Citlali, Stucchi, Riccardo, Altelaar, Maarten, Hoogenraad, Casper C.
Format: Artigo
Language:Inglês
Published: Cell Press 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907685/
https://ncbi.nlm.nih.gov/pubmed/33571451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2021.01.010
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