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JIP3 Mediates TrkB Axonal Anterograde Transport and Enhances BDNF Signaling by Directly Bridging TrkB with Kinesin-1

Brain-derived neurotrophic factor (BDNF), secreted from target tissues, binds and activates TrkB receptors, located on axonal terminals of the innervating neurons, and thereby initiates retrograde signaling. Long-range anterograde transport of TrkB in axons and dendrites requires kinesin-mediated tr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Huang, Shu-Hong, Duan, Shan, Sun, Tao, Wang, Jue, Zhao, Ling, Geng, Zhao, Yan, Jing, Sun, Hai-Ji, Chen, Zhe-Yu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622626/
https://ncbi.nlm.nih.gov/pubmed/21775604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0436-11.2011
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