Berberine Promotes Induction of Immunological Tolerance to an Allograft via Downregulating Memory CD8(+) T-Cells Through Altering the Gut Microbiota

Emerging evidence has linked the gut microbiota dysbiosis to transplant rejection while memory T-cells pose a threat to long-term transplant survival. However, it's unclear if the gut microbiome alters the formation and function of alloreactive memory T-cells. Here we studied the effects of ber...

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Udgivet i:Front Immunol
Main Authors: Qiu, Feifei, Lu, Weihui, Ye, Shulin, Liu, Huazhen, Zeng, Qiaohuang, Huang, Haiding, Liang, Chun-Ling, Chen, Yuchao, Zheng, Fang, Zhang, Qunfang, Lu, Chuan-Jian, Dai, Zhenhua
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907598/
https://ncbi.nlm.nih.gov/pubmed/33643325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.646831
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