Resveratrol exerts antitumor effects by downregulating CD8(+)CD122(+) Tregs in murine hepatocellular carcinoma

CD4(+)Foxp3(+) regulatory T cells (Tregs) in the tumor microenvironment restrain antitumor immunity, resulting in tumor aggression and poor survival in hepatocellular carcinoma (HCC). CD8(+)CD122(+) Tregs have been previously shown to be more potent in immunosuppression than are CD4(+)Foxp3(+) Tregs...

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Publicat a:Oncoimmunology
Autors principals: Zhang, Qunfang, Huang, Haiding, Zheng, Fang, Liu, Huazhen, Qiu, Feifei, Chen, Yuchao, Liang, Chun-Ling, Dai, Zhenhua
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588216/
https://ncbi.nlm.nih.gov/pubmed/33150044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1829346
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