TGF-β-Induced Endothelial to Mesenchymal Transition Is Determined by a Balance Between SNAIL and ID Factors

Endothelial-to-mesenchymal transition (EndMT) plays an important role in embryonic development and disease progression. Yet, how different members of the transforming growth factor-β (TGF-β) family regulate EndMT is not well understood. In the current study, we report that TGF-β2, but not bone morph...

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Bibliographic Details
Published in:Front Cell Dev Biol
Main Authors: Ma, Jin, van der Zon, Gerard, Gonçalves, Manuel A. F. V., van Dinther, Maarten, Thorikay, Midory, Sanchez-Duffhues, Gonzalo, ten Dijke, Peter
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907445/
https://ncbi.nlm.nih.gov/pubmed/33644053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.616610
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