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Iohexol plasma clearance simplified by Dried Blood Spot (DBS) sampling to measure renal function in conscious mice

There is no simple method to measure glomerular filtration rate (GFR) in mice, which limits the use of mice in models of renal diseases. We aimed at simplifying the plasma clearance of iohexol in mice, using dried blood spot (DBS) sampling in order to reduce the amount of blood taken for analysis. G...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rodríguez-Rodríguez, Ana Elena, Luis-Lima, Sergio, Donate-Correa, Javier, Diaz-Martín, Laura, Arnau, María Rosa, Jiménez-Sosa, Alejandro, Gaspari, Flavio, Ortiz, Alberto, Porrini, Esteban
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907335/
https://ncbi.nlm.nih.gov/pubmed/33633207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83934-2
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