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Iohexol plasma clearance simplified by Dried Blood Spot (DBS) sampling to measure renal function in conscious mice

There is no simple method to measure glomerular filtration rate (GFR) in mice, which limits the use of mice in models of renal diseases. We aimed at simplifying the plasma clearance of iohexol in mice, using dried blood spot (DBS) sampling in order to reduce the amount of blood taken for analysis. G...

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Publicat a:Sci Rep
Autors principals: Rodríguez-Rodríguez, Ana Elena, Luis-Lima, Sergio, Donate-Correa, Javier, Diaz-Martín, Laura, Arnau, María Rosa, Jiménez-Sosa, Alejandro, Gaspari, Flavio, Ortiz, Alberto, Porrini, Esteban
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907335/
https://ncbi.nlm.nih.gov/pubmed/33633207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83934-2
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