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The Putative Role of mTOR Inhibitors in Non-tuberous Sclerosis Complex-Related Epilepsy

Epilepsy affects ~5 out of every 10,000 children per year. Up to one-third of these children have medically refractory epilepsy, with limited to no options for improved seizure control. mTOR, a ubiquitous 289 kDa serine/threonine kinase in the phosphatidylinositol 3-kinase (PI3K)-related kinases (PI...

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Détails bibliographiques
Publié dans:Front Neurol
Auteurs principaux: Goldstein, Hannah E., Hauptman, Jason S.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907183/
https://ncbi.nlm.nih.gov/pubmed/33643212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.639319
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