AOA-2 Derivatives as Outer Membrane Protein A Inhibitors for Treatment of Gram-Negative Bacilli Infections

Previously, we identified that a cyclic hexapeptide AOA-2 inhibited the interaction of Gram-negative bacilli (GNB) like Acinetobacter baumannii, Pseudomonas aeruginosa, and Escherichia coli to host cells thereby preventing the development of infection in vitro and in a murine sepsis peritoneal model...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Microbiol
Prif Awduron: Ayerbe-Algaba, Rafael, Bayó, Nuria, Verdú, Ester, Parra-Millán, Raquel, Seco, Jesús, Teixidó, Meritxell, Pachón, Jerónimo, Giralt, Ernest, Smani, Younes
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021
Pynciau:
Microbiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907166/
https://ncbi.nlm.nih.gov/pubmed/33643267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.634323
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