Combating virulence of Gram-negative bacilli by OmpA inhibition

Preventing the adhesion of pathogens to host cells provides an innovative approach to tackling multidrug-resistant bacteria. In this regard, the identification of outer membrane protein A (OmpA) as a key bacterial virulence factor has been a major breakthrough. The use of virtual screening helped us...

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Udgivet i:Sci Rep
Main Authors: Vila-Farrés, Xavier, Parra-Millán, Raquel, Sánchez-Encinales, Viviana, Varese, Monica, Ayerbe-Algaba, Rafael, Bayó, Nuria, Guardiola, Salvador, Pachón-Ibáñez, María Eugenia, Kotev, Martin, García, Jesús, Teixidó, Meritxell, Vila, Jordi, Pachón, Jerónimo, Giralt, Ernest, Smani, Younes
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666006/
https://ncbi.nlm.nih.gov/pubmed/29089624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14972-y
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