Immunostimulatory nanoparticle incorporating two immune agonists for the treatment of pancreatic tumors

Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant disease, where even surgical resection and aggressive chemotherapy produce dismal outcomes. Immunotherapy is a promising alternative to conventional treatments, possessing the ability to elicit T cell-mediated killing of tumor cells and p...

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Udgivet i:J Control Release
Main Authors: Lorkowski, M.E., Atukorale, P.U., Bielecki, P.A., Tong, K.H., Covarrubias, G., Zhang, Y., Loutrianakis, G., Moon, T.J., Santulli, A.R., Becicka, W.M., Karathanasis, E.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906920/
https://ncbi.nlm.nih.gov/pubmed/33188827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.11.014
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