Nanoparticle encapsulation of synergistic immune agonists enables systemic co-delivery to tumor sites and interferon β-driven anti-tumor immunity

Effective cancer immunotherapy depends on the robust activation of tumor-specific antigen-presenting cells (APCs). Immune agonists encapsulated within nanoparticles can be delivered to tumor sites to generate powerful anti-tumor immune responses with minimal off-target dissemination. Systemic delive...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Atukorale, Prabhani U., Raghunathan, Shruti P., Raguveer, Vanitha, Moon, Taylor J., Zheng, Carolyn, Bielecki, Peter A., Wiese, Michelle L., Goldberg, Amy L., Covarrubias, Gil, Hoimes, Christopher J., Karathanasis, Efstathios
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801091/
https://ncbi.nlm.nih.gov/pubmed/31431457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0381
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