Lataa...
Discovery of sultam-containing small-molecule disruptors of the huntingtin—calmodulin protein—protein interaction
The aberrant protein—protein interaction between calmodulin and mutant huntingtin protein in Huntington’s disease patients has been found to contribute to Huntington’s disease progression. A high-throughput screen for small molecules capable of disrupting this interaction revealed a sultam series as...
Tallennettuna:
| Julkaisussa: | Med Chem Res |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2020
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7906539/ https://ncbi.nlm.nih.gov/pubmed/33642842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-020-02583-8 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|