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Indole C6 Functionalization of Tryprostatin B Using Prenyltransferase CdpNPT
Tryprostatin A and B are prenylated, tryptophan-containing, diketopiperazine natural products, displaying cytotoxic activity through different mechanisms of action. The presence of the 6-methoxy substituent on the indole moiety of tryprostatin A was shown to be essential for the dual inhibition of t...
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| Publicado no: | Catalysts |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7906295/ https://ncbi.nlm.nih.gov/pubmed/33643664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/catal10111247 |
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