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DNA methylation based glioblastoma subclassification is related to tumoral T-cell infiltration and patient survival

BACKGROUND: Histologically classified glioblastomas (GBM) can have different clinical behavior and response to therapy, for which molecular subclassifications have been proposed. We evaluated the relationship of epigenetic GBM subgroups with immune cell infiltrations, systemic immune changes during...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Dejaegher, Joost, Solie, Lien, Hunin, Zoé, Sciot, Raf, Capper, David, Siewert, Christin, Van Cauter, Sofie, Wilms, Guido, van Loon, Johan, Ectors, Nadine, Fieuws, Steffen, Pfister, Stefan M, Van Gool, Stefaan W, De Vleeschouwer, Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906065/
https://ncbi.nlm.nih.gov/pubmed/33130898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa247
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