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DNA methylation based glioblastoma subclassification is related to tumoral T-cell infiltration and patient survival

BACKGROUND: Histologically classified glioblastomas (GBM) can have different clinical behavior and response to therapy, for which molecular subclassifications have been proposed. We evaluated the relationship of epigenetic GBM subgroups with immune cell infiltrations, systemic immune changes during...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Dejaegher, Joost, Solie, Lien, Hunin, Zoé, Sciot, Raf, Capper, David, Siewert, Christin, Van Cauter, Sofie, Wilms, Guido, van Loon, Johan, Ectors, Nadine, Fieuws, Steffen, Pfister, Stefan M, Van Gool, Stefaan W, De Vleeschouwer, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906065/
https://ncbi.nlm.nih.gov/pubmed/33130898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa247
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