GLP-1 improves the supportive ability of astrocytes to neurons by promoting aerobic glycolysis in Alzheimer's disease

OBJECTIVE: Astrocytes actively participate in energy metabolism in the brain, and astrocytic aerobic glycolysis disorder is associated with the pathology of Alzheimer's disease (AD). GLP-1 has been shown to improve cognition in AD; however, the mechanism remains unclear. The objectives of this...

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Bibliographic Details
Published in:Mol Metab
Main Authors: Zheng, Jiaping, Xie, Yunzhen, Ren, Lingjia, Qi, Liqin, Wu, Li, Pan, Xiaodong, Zhou, Jianxing, Chen, Zhou, Liu, Libin
Format: Artigo
Language:Inglês
Published: Elsevier 2021
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905479/
https://ncbi.nlm.nih.gov/pubmed/33556642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101180
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