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Activity-dependent neuronal Klotho enhances astrocytic aerobic glycolysis

Mutations of the β-glucuronidase protein α-Klotho have been associated with premature aging, and altered cognitive function. Although highly expressed in specific areas of the brain, Klotho functions in the central nervous system remain unknown. Here, we show that cultured hippocampal neurons respon...

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Détails bibliographiques
Publié dans:J Cereb Blood Flow Metab
Auteurs principaux: Mazucanti, Caio H, Kawamoto, Elisa M, Mattson, Mark P, Scavone, Cristoforo, Camandola, Simonetta
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681535/
https://ncbi.nlm.nih.gov/pubmed/29493420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18762700
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