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Senescent Mesenchymal Stem Cells in Myelodysplastic Syndrome: Functional Alterations, Molecular Mechanisms, and Therapeutic Strategies

Myelodysplastic syndrome (MDS) is a group of clonal hematopoietic disorders related to hematopoietic stem and progenitor cell dysfunction. However, therapies that are currently used to target hematopoietic stem cells are not effective. These therapies are able to slow the evolution toward acute myel...

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發表在:Front Cell Dev Biol
Main Authors: Chen, Xiaofang, Li, Ningyu, Weng, Jianyu, Du, Xin
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905046/
https://ncbi.nlm.nih.gov/pubmed/33644035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.617466
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