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Accurate imputation of human leukocyte antigens with CookHLA

The recent development of imputation methods enabled the prediction of human leukocyte antigen (HLA) alleles from intergenic SNP data, allowing studies to fine-map HLA for immune phenotypes. Here we report an accurate HLA imputation method, CookHLA, which has superior imputation accuracy compared to...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Cook, Seungho, Choi, Wanson, Lim, Hyunjoon, Luo, Yang, Kim, Kunhee, Jia, Xiaoming, Raychaudhuri, Soumya, Han, Buhm
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904773/
https://ncbi.nlm.nih.gov/pubmed/33627654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21541-5
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