Accurate imputation of human leukocyte antigens with CookHLA

The recent development of imputation methods enabled the prediction of human leukocyte antigen (HLA) alleles from intergenic SNP data, allowing studies to fine-map HLA for immune phenotypes. Here we report an accurate HLA imputation method, CookHLA, which has superior imputation accuracy compared to...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Cook, Seungho, Choi, Wanson, Lim, Hyunjoon, Luo, Yang, Kim, Kunhee, Jia, Xiaoming, Raychaudhuri, Soumya, Han, Buhm
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904773/
https://ncbi.nlm.nih.gov/pubmed/33627654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21541-5
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