Oral Delivery of Metformin by Chitosan Nanoparticles for Polycystic Kidney Disease

Nanoparticle drug delivery has many advantages over small molecule therapeutics, including reducing off-target side effects and increasing drug potency. However, many nanoparticles are administered parenterally, which is challenging for chronic diseases such as polycystic kidney disease (PKD), the m...

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Опубликовано в: :J Control Release
Главные авторы: Wang, Jonathan, Chin, Deborah, Poon, Christopher, Mancino, Valeria, Pham, Jessica, Li, Hui, Ho, Pei-Yin, Hallows, Kenneth R., Chung, Eun Ji
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904655/
https://ncbi.nlm.nih.gov/pubmed/33127449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.10.047
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