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Notch signaling induces either apoptosis or cell fate change in multiciliated cells during mucociliary tissue remodeling

Multiciliated cells (MCCs) are extremely highly-differentiated, presenting >100 cilia and basal bodies. Therefore, MCC fate is thought to be terminal and irreversible. We analyzed how MCCs are removed from the airway-like mucociliary Xenopus epidermis during developmental tissue remodeling. We fo...

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Publicat a:Dev Cell
Autors principals: Tasca, Alexia, Helmstädter, Martin, Brislinger, Magdalena, Haas, Maximilian, Mitchell, Brian, Walentek, Peter
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904641/
https://ncbi.nlm.nih.gov/pubmed/33400913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.12.005
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