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17β-estradiol activation of dorsal hippocampal TrkB is independent of increased mature BDNF expression and is required for enhanced memory consolidation in female mice
The potent estrogen 17β-estradiol (E(2)) is known to enhance hippocampal memory and plasticity, however the molecular mechanisms underlying these effects remain unclear. Brain derived neurotrophic factor (BDNF) and its receptor tropomyosin receptor kinase B (TrkB) are regulated by E(2), but the pote...
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| Publicado no: | Psychoneuroendocrinology |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7904635/ https://ncbi.nlm.nih.gov/pubmed/33352471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2020.105110 |
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