Infralimbic Estradiol Enhances Neuronal Excitability and Facilitates Extinction of Cocaine Seeking in Female Rats via a BDNF/TrkB Mechanism

Women are more susceptible to developing cocaine dependence than men, but paradoxically, are more responsive to treatment. The potent estrogen, 17β-estradiol (E(2)), mediates these effects by augmenting cocaine seeking but also promoting extinction of cocaine seeking through E(2)’s memory-enhancing...

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Dettagli Bibliografici
Pubblicato in:Front Behav Neurosci
Autori principali: Yousuf, Hanna, Smies, Chad W., Hafenbreidel, Madalyn, Tuscher, Jennifer J., Fortress, Ashley M., Frick, Karyn M., Mueller, Devin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684748/
https://ncbi.nlm.nih.gov/pubmed/31417375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2019.00168
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