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INHIBITION OF THE VESICULAR GLUTAMATE TRANSPORTER (VGLUT) WITH CONGO RED ANALOGS: NEW BINDING INSIGHTS.

The vesicular glutamate transporter (VGLUT) facilitates the uptake of glutamate (Glu) into neuronal vesicles. VGLUT has not yet been fully characterized pharmacologically but a body of work established that certain azo-dyes bearing two Glu isosteres via a linker were potent inhibitors. However, the...

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Publicat a:Neurochem Res
Autors principals: Hitt, David M., Zwicker, Jeffery D., Chao, Chih-Kai, Patel, Sarjubhai A., Gerdes, John M, Bridges, Richard J., Thompson, Charles M.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904594/
https://ncbi.nlm.nih.gov/pubmed/33398639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-020-03182-0
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