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Immunostimulatory TLR7 agonist-nanoparticles together with checkpoint blockade for effective cancer immunotherapy

Mono- or dual-checkpoint inhibitors for immunotherapy have changed the paradigm of cancer care; however, only a minority of patients responds to such treatment. Combining small molecule immuno-stimulators can improve treatment efficacy, but they are restricted by poor pharmacokinetics. In this study...

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Detalhes bibliográficos
Publicado no:Adv Ther (Weinh)
Main Authors: Huang, Ching-Hsin, Mendez, Natalie, Echeagaray, Oscar Hernandez, Weeks, Joi, Wang, James, Yao, Shiyin, Blair, Sarah L., Gude, Natalie, Trogler, William C., Carson, Dennis A., Hayashi, Tomoko, Kummel, Andrew C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904104/
https://ncbi.nlm.nih.gov/pubmed/33644299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adtp.201900200
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