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Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor

In order to produce proteins essential for their propagation, many pathogenic human viruses, including SARS-CoV-2, the causative agent of COVID-19 respiratory disease, commandeer host biosynthetic machineries and mechanisms. Three major structural proteins, the spike, envelope and membrane proteins,...

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Bibliographic Details
Published in:J Cell Sci
Main Authors: O'Keefe, Sarah, Roboti, Peristera, Duah, Kwabena B., Zong, Guanghui, Schneider, Hayden, Shi, Wei Q., High, Stephen
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904091/
https://ncbi.nlm.nih.gov/pubmed/33468620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.257758
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