Borrelidin from Saltern-Derived Halophilic Nocardiopsis sp. Dissociates Amyloid-β and Tau Fibrils

BACKGROUND: Alzheimer’s disease (AD) is characterized by the aggregation of two pathological proteins, amyloid-β (Aβ) and tau, leading to neuronal and cognitive dysfunction. Clearance of either Aβ or tau aggregates by immunotherapy has become a potential therapy, as these aggregates are found in the...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis Rep
Main Authors: Shin, Jisu, Yang, Seung-Hoon, Du, Young Eun, Park, Keunwan, Kim, DaWon, Shin, Daniel, Kim, Jungwoo, Kim, Seong-Hwan, Kim, Yun Kyung, Shin, Jongheon, Oh, Dong-Chan, Kim, YoungSoo
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2021
Assuntos:
Research Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7903018/
https://ncbi.nlm.nih.gov/pubmed/33681712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-200247
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