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Porphyromonas Gingivalis May Seek the Alzheimer’s Disease Brain to Acquire Iron from Its Surplus

Iron accumulates in the brain of subjects with Alzheimer’s disease (AD). Here it promotes the aggregation of amyloid-β plaques in which it is abundant. Iron induces amyloid-β neurotoxicity by damaging free radicals and causing oxidative stress in brain areas with neurodegeneration. It can also bind...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Alzheimers Dis Rep
1. Verfasser: Olsen, Ingar
Format: Artigo
Sprache:Inglês
Veröffentlicht: IOS Press 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7903007/
https://ncbi.nlm.nih.gov/pubmed/33681719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-200272
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