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Porphyromonas Gingivalis May Seek the Alzheimer’s Disease Brain to Acquire Iron from Its Surplus

Iron accumulates in the brain of subjects with Alzheimer’s disease (AD). Here it promotes the aggregation of amyloid-β plaques in which it is abundant. Iron induces amyloid-β neurotoxicity by damaging free radicals and causing oxidative stress in brain areas with neurodegeneration. It can also bind...

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Podrobná bibliografie
Vydáno v:J Alzheimers Dis Rep
Hlavní autor: Olsen, Ingar
Médium: Artigo
Jazyk:Inglês
Vydáno: IOS Press 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7903007/
https://ncbi.nlm.nih.gov/pubmed/33681719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-200272
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