Challenges and Clinical Strategies of CAR T-Cell Therapy for Acute Lymphoblastic Leukemia: Overview and Developments

Chimeric antigen receptor (CAR) T-cell therapy exhibits desirable and robust efficacy in patients with acute lymphoblastic leukemia (ALL). Stimulated by the revolutionized progress in the use of FDA-approved CD19 CAR T cells, novel agents with CAR designs and targets are being produced in pursuit of...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Xu, Xinjie, Huang, Shengkang, Xiao, Xinyi, Sun, Qihang, Liang, Xiaoqian, Chen, Sifei, Zhao, Zijing, Huo, Zhaochang, Tu, Sanfang, Li, Yuhua
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902522/
https://ncbi.nlm.nih.gov/pubmed/33643279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.569117
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