Challenges and Clinical Strategies of CAR T-Cell Therapy for Acute Lymphoblastic Leukemia: Overview and Developments

Chimeric antigen receptor (CAR) T-cell therapy exhibits desirable and robust efficacy in patients with acute lymphoblastic leukemia (ALL). Stimulated by the revolutionized progress in the use of FDA-approved CD19 CAR T cells, novel agents with CAR designs and targets are being produced in pursuit of...

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Опубликовано в: :Front Immunol
Главные авторы: Xu, Xinjie, Huang, Shengkang, Xiao, Xinyi, Sun, Qihang, Liang, Xiaoqian, Chen, Sifei, Zhao, Zijing, Huo, Zhaochang, Tu, Sanfang, Li, Yuhua
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902522/
https://ncbi.nlm.nih.gov/pubmed/33643279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.569117
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