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Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD

Allogeneic haematopoietic stem cell transplantation (allo-HSCT) was the first successful therapy for patients with haematological malignancies, predominantly owing to graft-versus-tumour (GvT) effects. Dramatic methodological changes, designed to expand eligibility for allo-HSCT to older patients an...

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Publicat a:Nat Rev Clin Oncol
Autors principals: Blazar, Bruce R., Hill, Geoffrey R., Murphy, William J.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901860/
https://ncbi.nlm.nih.gov/pubmed/32313224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41571-020-0356-4
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