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Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta—Brief Report

OBJECTIVE: Efficient gene transfer to the vascular wall via intravenous vector injection would be useful for experimental vascular biology and gene therapy. Initial studies of lentiviral vector tropism suggested that intravenously injected vectors do not transduce murine vascular tissue; however, th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arterioscler Thromb Vasc Biol
Prif Awduron: Bi, Lianxiang, Wacker, Bradley K., Stamatikos, Alexis, Sethuraman, Meena, Komandur, Kaushik, Dichek, David A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Lippincott Williams & Wilkins 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901533/
https://ncbi.nlm.nih.gov/pubmed/33297756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.315125
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