Deletion of Orphan G Protein-Coupled Receptor GPR37L1 in Mice Alters Cardiovascular Homeostasis in a Sex-Specific Manner

GPR37L1 is a family A orphan G protein-coupled receptor (GPCR) with a putative role in blood pressure regulation and cardioprotection. In mice, genetic ablation of Gpr37l1 causes sex-dependent effects; female mice lacking Gpr37l1 (GPR37L1(−/−)) have a modest but significant elevation in blood pressu...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Mouat, Margaret A., Jackson, Kristy L., Coleman, James L. J., Paterson, Madeleine R., Graham, Robert M., Head, Geoffrey A., Smith, Nicola J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901490/
https://ncbi.nlm.nih.gov/pubmed/33633567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.600266
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