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Reactive Myelopoiesis and the Onset of Myeloid-Mediated Immune Suppression: Implications for Adoptive Cell Therapy

Adoptive T cell therapy (ACT) in combination with lymphodepleting chemotherapy is an effective strategy to induce the eradication of cancer, providing long-term regressions in patients. However, only a minority of patients that receive ACT with tumor-specific T cells exhibit durable benefit. Thus, t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Immunol
Hauptverfasser: Innamarato, Patrick, Pilon-Thomas, Shari
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901256/
https://ncbi.nlm.nih.gov/pubmed/33476931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2020.104277
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