Systemic administration of β-glucan induces immune training in microglia

BACKGROUND: An innate immune memory response can manifest in two ways: immune training and immune tolerance, which refers to an enhanced or suppressed immune response to a second challenge, respectively. Exposing monocytes to moderate-to-high amounts of bacterial lipopolysaccharide (LPS) induces imm...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Heng, Yang, Zhang, Xiaoming, Borggrewe, Malte, van Weering, Hilmar R. J., Brummer, Maaike L., Nijboer, Tjalling W., Joosten, Leo A. B., Netea, Mihai G., Boddeke, Erik W. G. M., Laman, Jon D., Eggen, Bart J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901224/
https://ncbi.nlm.nih.gov/pubmed/33618716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02103-4
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