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The cytokine network Type I Interferon, IL-27 and IL-10 is augmented in murine and human lupus.
Interleukin (IL)-10 is elevated in the autoimmune disease systemic lupus erythematosus (SLE). Here we show that conventional dendritic cells (cDCs) from pre-disease lupus-prone B6.NZM Sle1/Sle2/Sle3 triple congenic (TCSle) mice produce more IL-10 than wild type congenic cDCs upon TLR stimulation, an...
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| Publicado no: | J Leukoc Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7901002/ https://ncbi.nlm.nih.gov/pubmed/31216373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3AB0518-180RR |
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