Abnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupus

We analyzed the activation and function of dendritic cells (DCs) in the spleens of diseased, lupus-prone NZM2410 and NZB-W/F1 mice and age-matched BALB/c and C57BL/6 control mice. Lupus DCs showed an altered ex vivo costimulatory profile, with a significant increase in the expression of CD40, decrea...

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Detalhes bibliográficos
Main Authors: Colonna, Lucrezia, Dinnall, Joudy-Ann, Shivers, Debra K, Frisoni, Lorenza, Caricchio, Roberto, Gallucci, Stefania
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1526610/
https://ncbi.nlm.nih.gov/pubmed/16507174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1911
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