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Sleuthing biochemical evidence to elucidate unassigned electron density in a CBL–SLAP2 crystal complex
The Src-like adaptor proteins (SLAP/SLAP2) bind to CBL E3 ubiquitin ligase to downregulate antigen, cytokine and tyrosine kinase receptor signalling. In contrast to the phosphotyrosine-dependent binding of CBL substrates through its tyrosine kinase-binding domain (TKBD), CBL TKBD associates with the...
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| Yayımlandı: | Acta Crystallogr F Struct Biol Commun |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
International Union of Crystallography
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7900928/ https://ncbi.nlm.nih.gov/pubmed/33620036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X21000911 |
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