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Clinicopathologic profile, immunophenotype, and genotype of CD274 (PD-L1)-positive colorectal carcinomas

The CD274 (PD-L1)/PDCD1 (PD-1) pathway is crucial for the modulation of immune responses and self-tolerance. Aberrantly expressed CD274 allows tumor cells to evade host immune system and is considered to be a mechanism of adaptive immune resistance. Inhibition of the CD274/PDCD1 immune checkpoint of...

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Détails bibliographiques
Publié dans:Mod Pathol
Auteurs principaux: Inaguma, Shingo, Lasota, Jerzy, Wang, Zengfeng, Felisiak-Golabek, Anna, Ikeda, Hiroshi, Miettinen, Markku
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900912/
https://ncbi.nlm.nih.gov/pubmed/27813511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2016.185
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