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Binding of the human antioxidation protein α(1)-microglobulin (A1M) to heparin and heparan sulfate. Mapping of binding site, molecular and functional characterization, and co-localization in vivo and in vitro

Heparin and heparan sulfate (HS) are linear sulfated disaccharide polymers. Heparin is found mainly in mast cells, while heparan sulfate is found in connective tissue, extracellular matrix and on cell membranes in most tissues. α(1)-microglobulin (A1M) is a ubiquitous protein with thiol-dependent an...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Bergwik, Jesper, Kristiansson, Amanda, Larsson, Jörgen, Ekström, Simon, Åkerström, Bo, Allhorn, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900767/
https://ncbi.nlm.nih.gov/pubmed/33607500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101892
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