Brain‐derived neurotropic factor mediates neuroprotection of mesenchymal stem cell‐derived extracellular vesicles against severe intraventricular hemorrhage in newborn rats

Brain‐derived neurotropic factor (BDNF), which is secreted by mesenchymal stem cells (MSCs), protects against severe intraventricular hemorrhage (IVH)‐induced brain injuries. Although the paracrine protective effects of MSCs are mediated primarily by extracellular vesicles (EVs), the therapeutic eff...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Ahn, So Yoon, Sung, Dong Kyung, Kim, Young Eun, Sung, Sein, Chang, Yun Sil, Park, Won Soon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Cell Based Drug Development, Screening, and Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900593/
https://ncbi.nlm.nih.gov/pubmed/33319929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.20-0301
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