Brain‐derived neurotropic factor mediates neuroprotection of mesenchymal stem cell‐derived extracellular vesicles against severe intraventricular hemorrhage in newborn rats

Brain‐derived neurotropic factor (BDNF), which is secreted by mesenchymal stem cells (MSCs), protects against severe intraventricular hemorrhage (IVH)‐induced brain injuries. Although the paracrine protective effects of MSCs are mediated primarily by extracellular vesicles (EVs), the therapeutic eff...

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Bibliografiska uppgifter
I publikationen:Stem Cells Transl Med
Huvudupphovsmän: Ahn, So Yoon, Sung, Dong Kyung, Kim, Young Eun, Sung, Sein, Chang, Yun Sil, Park, Won Soon
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley & Sons, Inc. 2020
Ämnen:
Cell Based Drug Development, Screening, and Toxicology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900593/
https://ncbi.nlm.nih.gov/pubmed/33319929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.20-0301
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