Complex biology of constitutional ring chromosomes structure and (in)stability revealed by somatic cell reprogramming

Human ring chromosomes are often unstable during mitosis, and daughter cells can be partially or completely aneuploid. We studied the mitotic stability of four ring chromosomes, 8, 13, 18, and 22, in long-term cultures of skin fibroblasts and induced pluripotent stem cells (iPSCs) by GTG karyotyping...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nikitina, T. V., Kashevarova, A. A., Gridina, M. M., Lopatkina, M. E., Khabarova, A. A., Yakovleva, Yu. S., Menzorov, A. G., Minina, Yu. A., Pristyazhnyuk, I. E., Vasilyev, S. A., Fedotov, D. A., Serov, O. L., Lebedev, I. N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900208/
https://ncbi.nlm.nih.gov/pubmed/33619287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83399-3
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