Human Bile Contains Cholangiocyte Organoid-Initiating Cells Which Expand as Functional Cholangiocytes in Non-canonical Wnt Stimulating Conditions

Diseases of the bile duct (cholangiopathies) remain a common indication for liver transplantation, while little progress has been made over the last decade in understanding the underlying pathophysiology. This is largely due to lack of proper in vitro model systems to study cholangiopathies. Recentl...

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Dades bibliogràfiques
Publicat a:Front Cell Dev Biol
Autors principals: Roos, Floris J. M., Verstegen, Monique M. A., Muñoz Albarinos, Laura, Roest, Henk P., Poley, Jan-Werner, Tetteroo, Geert W. M., IJzermans, Jan N. M., van der Laan, Luc J. W.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900156/
https://ncbi.nlm.nih.gov/pubmed/33634107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.630492
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