Digital PCR for high sensitivity viral detection in false-negative SARS-CoV-2 patients

Patients requiring diagnostic testing for coronavirus disease 2019 (COVID-19) are routinely assessed by reverse-transcription quantitative polymerase chain reaction (RT-qPCR) amplification of Sars-CoV-2 virus RNA extracted from oro/nasopharyngeal swabs. Despite the good specificity of the assays cer...

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izdano v:Sci Rep
Main Authors: Poggio, Paolo, Songia, Paola, Vavassori, Chiara, Ricci, Veronica, Banfi, Cristina, Barbieri, Silvia Stella, Garoffolo, Gloria, Myasoedova, Veronika A., Piacentini, Luca, Raucci, Angela, Scopece, Alessandro, Sommariva, Elena, Vinci, Maria Cristina, Carcione, Davide, Biondi, Maria Luisa, Mancini, Maria Elisabetta, Formenti, Alberto, Andreini, Daniele, Assanelli, Emilio M., Agostoni, Piergiuseppe, Camera, Marina, Colombo, Gualtiero I., Pesce, Maurizio
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900100/
https://ncbi.nlm.nih.gov/pubmed/33619321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83723-x
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